Justin Letendre
Senior Scientist - Synthetic Biology Strand Therapeutics Inc.
Justin is a synthetic biologist with expertise in genetic circuit design and is passionate about using synbio to program more targeted and effective therapies. As a Senior Scientist of Synthetic Biology at Strand, his work centers around understanding how to leverage the unique microRNA signatures of different cell phenotypes to define how therapies will be targeted to and operate in each cell. Before joining Strand, Justin completed his Ph.D. at Boston University where he developed gene circuits to implement complex signal processing programs and cell-cell communication systems in mammalian cells. Additionally, he holds a M.S. from Boston University and B.S. from the University of Connecticut, both in biomedical engineering. Justin’s work has been featured in several high-impact peer-reviewed journals including Cell, Nature Communications Biology, and Circulation.
Seminars
- Demonstrate translational insights from STX-001 to validate tolerability, expression durability and clinical feasibility of replicating RNA as a therapeutic modality
- Unlocking extrahepatic therapeutic opportunities with STX-003 through delivery-agnostic gene circuits that enhance tissue specificity, minimize off-target activity and broaden indication scope
- Enabling more complex and potent therapeutic designs by integrating replicating RNA architecture with programmable gene circuits to achieve controlled, high-impact expression in vivo
