Darina Spasova
Senior Scientific Director Replicate Bioscience
Seminars
Wednesday 27th May 2026
Delivering Self-Amplifying RNA Rabies Vaccines to Achieve Durable Clinical Protection
12:00 pm
- Demonstrate how self-amplifying RNA design produces robust immune responses, using rabies as a model indication with defined correlates of protection
- Uncover how enhanced antigen expression drives longer-lasting immunity, addressing the short durability of existing rabies vaccines
- Share clinical translation learnings that de-risk RNA vaccine development, including dosing strategy, durability assessment, and endpoint alignment
