Covadonga Paneda
Chief Operating Officer Altamira Therapeutics
Seminars
Wednesday 27th May 2026
Panel: Comparing Delivery Architectures to Match Modalities to Indication Needs
4:15 pm
- Debate core trade-offs including tropism, immunogenicity, manufacturability, payload size, and dosing frequency across LNP, AAV, and novel options
- Determine best-fit delivery platforms for CNS, immune modulation, oncology, hepatic, and neuromuscular indications
- Address LNP partnership models that support predictable GMP supply and scalable therapeutic development
Wednesday 27th May 2026
Advancing Peptide-Based circRNA Delivery to Enable Extrahepatic, Inflammation-Tolerant RNA Therapeutics
3:45 pm
- Demonstrate delivery compatibility and performance of circular RNA by using xPhore™ peptide-based nanoparticles to achieve efficient cellular uptake and expression across multiple cell types
- Differentiate circRNA and linear mRNA applications through head-to-head delivery comparisons, highlighting how identical delivery architectures reveal modality-specific expression profiles and use-case fit
- Expand RNA therapeutic reach beyond LNP-dominated paradigms by enabling extrahepatic and inflammation-tolerant delivery suitable for tissues poorly served by conventional lipid-based systems
