Mapping the RNA Landscape to Strengthen Strategy for Next-Generation Circular & Self-Amplifying Therapeutics

  • Establish a clear foundational understanding of RNA modality evolution from linear mRNA to circular and self-amplifying formats to guide early strategic platform selection
  • Identify where circRNA and saRNA deliver meaningful scientific and clinical advantages to help teams prioritize programs with the highest translational potential
  • Illustrate the structural, durability and immunological trade-offs across RNA formats in key areas such as cell therapy and immunotherapy to contextualize upcoming case studies