Harnessing Cascade Amplification & Therapeutic Payload (CATP) Systems to Unlock Potent, Low-Dose & Multi-Payload saRNA Therapeutics

  • Achieve strong therapeutic expression at lower doses using a two-step amplification system that combines saRNA with defective viral replication to bypass current safety– efficacy limits
  • Enable multi-gene and complex therapeutic logic through a dual-amplification system capable of supporting larger and more sophisticated payloads beyond traditional vaccine applications
  • Improve targeting precision and reduce off-target liver accumulation with advanced delivery design that supports tissue- and cell-type–specific uptake for safer, more predictable translation